SLU-PP-332

SLU-PP-332 is a research-grade oral small molecule agonist of estrogen-related receptor (ERR) proteins, specifically ERRα. This compound is designed for experimental studies focusing on mitochondrial biogenesis, exercise mimetic effects, and metabolic endurance within muscle and energy homeostasis models. By activating PGC-1α coactivator pathways, SLU-PP-332 facilitates investigations into enhanced fat oxidation, oxidative capacity, and performance adaptations that occur independently of physical training.

Research Applications

• Investigates the impact of SLU-PP-332 on mitochondrial density and function in skeletal muscle fibers, with preclinical studies suggesting improved endurance, fatty acid utilization, and resistance to fatigue in sedentary models.
• Explores the compound’s role in enhancing metabolic flexibility through the upregulation of type I fiber characteristics, contributing to research on obesity reversal, insulin sensitivity, and aerobic capacity.
• Examines the potential of SLU-PP-332 to elevate whole-body energy expenditure, making it a valuable tool for studying sarcopenia prevention and training augmentation in aging populations.

For research and laboratory use only. Not for human consumption.